I keep using Wonafyt early-game if I find it, helps me conserve regen and/or create nice little non-blocking monster/blood pool gardens for later.
Attacking monsters equal or lower level than you is a significant opportunity cost in lost bonus XP, far exceeding what you lose to exploration. The blood pool problem no longer applies, either, now that they are no longer drained if you are at full health. Furthermore, this glyph is positively pointless once you've explored about a third of the map, which should give you a wide
selection of monsters that are lower-level than you to attack, so there's no longer any purpose to using it. A glyph that's completely useless that early in the game needs
revamping, end of story.
The main reason Wonafyt and Byseps are seen as weak is that you're all relying on items that are too strong
I disagree; BYSSEPS is currently synergizing
with the overpowered Trisword, and doesn't really stand to gain or lose from items getting weaker in general. Furthermore, the fundamental issue remains that it's competing for valuable and limited inventory space; even with weaker items that competition doesn't change. As a non-stackable low-cost/low-gain effect, it's one of the first things to get converted as your inventory fills up.
Remember that conversion late game is not neccessarily a bad thing
But if it's always
converted late game that's a problem. Unless you're a wizard, the odds are that you're only going to find 2-3 glyphs in the early-game. This means there's a roughly 50% chance that a glyph will only be discovered once you're already a mid-level character. Especially given that glyphs like HALPMEH and CYDSTEPP perform very well at all
levels, I find it problematic to have too many glyphs that are strong early and weak late.
We already have ENDISWAL and BLUDTUPOWA which are exploration-based. We already have IMAWAL that stops being useful once you're no longer earning bonus XP to really cash in on that multiplier. We already have LEMMISI which just doesn't do much on many level layouts (was much
better in the alpha where most dungeons had lots of inaccessible tiles, but most beta dungeons have relatively few). We've got too much conversion fodder as it is.
Remember that conversion late game is not neccessarily a bad thing: You can't convert from shops, so finding a glyph you're not going to use is still good.
There are also loads of kick-ass early-game items
that will be hitting the conversion bin about this time. Pendant of Health, Gloves of Midas, Patches, Vampiric Blade... all of these stop performing in the end-game and get cycled out.