Then they would make the Pactmaker in Gaan-Telet instead of Horratio.
The Arena of the Gods would have a series of mini-floors (One per level) where you have to kill the boss at the end of each level. Like the bridge troll. No glyphs spawn.
The Chamber of Trickery would have twice as many monsters, but 1/2 of each level would secretly not give exp. Everything has first strike. There would be sorcerers, goats, goo blobs, snakes, acid blobs, and naga.
The Majestic Palace would have all monsters with 150% stats (Instead of the normal 133% for vicious) and all lower level monsters would disappear like the frigid corpses in the berserker camp.
The Land of Wild Magic: Random monsters, except spawner is slightly rigged toward wild magic which does 200% magical damage, weakening, and has 50% hp. An extra glyph spawns
The Inner Sanctum would have vampires, shades, wraiths, zombies, and muck walkers. They all revive into blood slaves which are corrosive zombies.
Earthmother's Grove would be all plants. Plants like fighting flameweed which have gorgon stats, first strike, and magical attack.
The Endless Mine would have tons of walls, but when mined they turn into a random level servant of rock which has meat man stats and berserk 50%. They follow you like revenants. ENDISWALL always spawns next to the player.
ThE cHaOs DiMeNsIoN is completely normal except that you randomly get hit by patches effects every few tiles.
I speak chaos.