I got AA on the 8th floor of my last run AND still managed to beat them anyway.
(Halfing Priest w/ Alchemist scroll, Dodging, 3 lvls Sanguine, Blood shield)
Then I get to Horatio and punk out when he is at 1/3 health. So depressing. Those AA's pillaged my resources, as I had to use every last blood pool to eke out a victory, leaving me with like 3 health potions to use to fight Horatio. I think I could have done it if I had found a Trisword on the first floor.
Damn, I hate those friggin' things.
On a side note, not sure if this is a bug or not, but the Alchemist Scroll resets every time I get level 10 "again".