At the very least, I'd say that the game needs to be better safeguarded against misclicks, specially with how it likes to get laggy on long dungeon runs.
Right now the game counts a click when you release the mouse button. One thing that ends up happening way too often is when you press and release the mouse button on top of a tile/menu, and then move the mouse away, and because of the lag the game acts as if I had released the mouse button wherever else my cursor is at the moment. Just lost a long vicious run because of that.
I'd suggest for the game to check that the cursor hasn't moved between pressing and releasing the mouse button, to avoid such unfortunate misclicks.