As far as venom dagger and tikki's poison are concerned, I don't have a problem with this new system. If venom dagger was 3 stacks per level and Tikki's poison boon was 3 stacks per level at 25+25 piety (with 10 gold) then I think we'd be in business. It's APHEELSIK this doesn't work for, since the entire basis of the glyph is being able to funnel an arbitrary amount of exploration space into utility spells so long as you can pay 7 MP between bursts. It might be workable with a sufficiently high stacking amount (say 50+20 per level) that it's unlimited for all intents and purposes, but let's not mince words: APHEELSIK did not
need a nerf and any meaningful reduction in its power needs to be matched with a meaningful improvement in another aspect.
Honestly I think making poison not remove stacks when monster is at full health would bring back power while embracing the new form. It would create a different playstyle from the spell but that isn't necessarily bad?
It wouldn't be feasible unless you also had BLUDTUPOWA, since you're wasting health-based regeneration while stacking up poison, making it an inefficient and fundamentally non-viable approach.
Second of all, we already have superb prebuff utility glyphs in the form of GETINDARE, ENDISWAL, BYSSEPS, and CYDSTEPP. I don't feel we need more.
Finally, I feel this suggestion has the potential to be a number-crunching nightmare, forcing players to do some pretty intensive calculations ahead of time regarding how many tiles they'll need for a takedown. Regen-fighting techniques are already pretty crunch-heavy, and if poison worked like this it would cross the line.