Oh, and before I forget, one of the lamest combos of all: Sorcerer/Specialist PQI
The Sorcerer's mana shield counts as a magical attack. As a result, a regular attack will deal both physical and magical damage and automatically fail the PQI. If you can't do an all-fireball or all-PISORF boss kill, the only way to pull it off is with cleansing to make your attack all magical in nature.