Just tried a Human Priest healthmonster of EM in Naga City using the damage reduction stacking idea. It doesn't dominate the way that a Rogue can, be it' still fun and effective. The worst part is scumming for the Platemail. You don't have to have it, but it's what makes the approach unique.
I left the surface with 100 piety, 38 DR and well over 200 health. Converted to Dracul and took two hits of Blood Hunger, upping my effective DR all the way to 58. A hit of Blood Tithe meshed well with my large health pool and is almost free. If you kept a burn salve on you, you can desecrate EM for more piety. After you've emptied you piety, take Consensus and escape to some other god that will let you use your potions. A health stacked human priest with the Keg of Health + Yendor from the arena is a beast, especially when you shrug off the first 58 points of every attack.
Fun facts about damage reduction versus resistance:
1) It isn't affected by the side effect of Blood Hunger
2) It stacks with Blood Hunger in a non-linear fashion
3) It is not affected by Binlor's wrath, giving you another desecration. Had I realized that earlier, I would have taken 3 hits of Blood Hunger and would have had an effective DR of 68.