I think your best shot is hitting as much lifesteal and DR as possible. Start with EM for DR (and buy/prep platemail), then go to anyone for anything else you want (making sure to get at least 10% resist all), then go to Drac for 2 lifesteals, blood shield if you aren't maxed on resists, and Sanguine. If you get 10 DR off EM that's 30 DR (-30 damage to 45), then 25% resists (-11 to 34), and a vampiric blade for 3 lifesteal (-30 to 4 damage), that leaves him doing 4 damage until he berserks. If you can pull that off you should be good between conversions, bloodstains, and blood cows. If you can score the orb of zot to combo with Whupaz it will be a walkover. That means with preps you have to scum for poison+mana burn immunities, Vampiric Blade, and the proper god order (EM early, and Drac not too late).
I used a simplified version of this to beat Mance (only platemail and lifesteal, plus zot whupaz combo).
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