It needs a lot of luck, but a fantastic combination is cydstepp + mid-high levels of poison strike. What is even better, the source can give you gettindare too.
In the optimal scenario you're running around with a 7 MP cydstepping, poisonous orc wizard with probably some knockback and a Rock Heart. If you visited Dracul, you could take some sanguine to decrease your HP, take Blood Curse to up your regen and poison as well. Add some lifesteal if resist stacking is not possible.
By using poison you don't need to decrease your health that much, if at all, and you regenerate MP back as well when you do this unique regen fighting. The best thing is, you can ignore your opponent's damage, and since you're regen fighting, his health too