Never tried it, but if I wanted to, I'd prep EM and a soul orb, and would spam entanglement too. My choosen class would be halfdragon, so I could push around plants without killing them.
That should be very effective at wasting space.
Too bad this map has no blinking monsters. I have weytwuted into sealed off, but discovered secret subdungeons before with the help of burn vipers. I'm not sure if it also works with plants, can't remember how EM places those.
Somebody spilled raspberry juice all over the place!