I was thinking more about Vicious Shops replacing your current Item Prep so that those combinations don't happen. "Hey instead of using my lockered item on this run today, how about I use a Vicious Shop instead?"
I would support this because I feel that being able to prep Vicious items makes the game too easy. I just unlocked Avatar's Codex and I just curbstomped Cursed Oasis as a Monk, which previously was finding incredibly difficult. I really would not mind paying for these items to prep them.