Might be possible, but since you're not allowed to kill anything (well, if you'r looking fr bonus) there's no bloodpools, and your glyphs are large and stuff. Wizard can bring in all the glyphs, which comes in right handy (I would've won had I used Endiswal properly, and Getindare + Byceps and deffinitely Apheelsick helped a ton). I think this used to be doable even back when wizard had it's -25% attack and way fewer perks.
In my honest opinion, they kinda ovebuffed the guy. I remember doing a huge rampage with the old wizard and the old crystal ball right before they nerfed edit: the CB and being surprised how underrated he was oposed to underpowered (we were comparing him to the still kinda dodgy Sorcerer and the old no-downside-whatsoever Bloodmage, though). I did kinda lean on the old, very silly CB during the course of said rampage, but it turns out that things' still pretty busted, and the Wizard got buffed, and NC got, well, nerfed and there you have it.
The challenge still isn't a walk in the park, but it's most likely highly doable. Biggest deal is managing your money for altar desecrations and all that, I think, and it does stop the CB for being even more of a complete menace, but I only did this on a lark, it wasn't a particularly serious attempt and I was about one major refill away from doing it without touching the popcorn.
It's likely that a Binlor magic res farmer could do it consistently with a bit of shop luck for mana items and Apheelsick. Swap into Mystera right away, take magic 2 times, consensus for refreshment, take Alchemist Pact and that ought to be that.
EDIT: Like this:
I had a sort of good subdungeon and the money secret sub - but no CB, which means I was, oh, let's say... half as powerful if were still trying to keep up the pretense that it isn't as busted as it actually is?
Anyway, so the challenge is - descend at lvl 1 with a Gnome and only kill the bossess. If you're using CB (I wasn't), then no shops down below for bonus points (shouldn't be a problem, really).
Anyone does it VT I'd be impressed, shops, popcorn and all. Even chea... I mean Crystal Ball.