I posted a two complaints about the new deity screen during the Enhanced Edition beta, and there was never a developer response on either issue. Given the length of time that's passed, I wanted to make a specific post on the issue.
Deity Hotkey No Longer Works
In the vanilla game you could press control to quickly bring up the deity menu. This functioned any time you were on the same dungeon level as your active altar and had pathing to it. Purchasing a boon was literally a matter of hitting control, clicking the boon you wanted, then releasing control. The new deity menu requires you to stand on the altar to enable the deity tab then mouse over a tab off in the corner of the screen. This makes it considerably less accessible and practical than the old version.
Glowing Guardian Prayer Beads cause you to change tabs
When you purchase a boon from the Glowing Guardian that causes you to gain a prayer bead it switches you to the inventory tab and away from the deity tab. This is annoying because all of these boons are repeatable, so if you want to take them multiple times in a row (very common for absolution and protection) you have to reset the tab every time.
If a fix isn't possible within the new interface, then please allow a toggle for the classic deity interface. I suspect most players weren't even aware of that hotkey, but for those of us who were using it the new interface is very much a downgrade because of the lost feature.