I'm still "waiting" for that Rogue daily which starts hard blocked, but somebody manages to get the required dodges to get past it.
I don't know if it is possible with the monster algorithm, but could Cursed Oasis have all low-level enemies (well, there could be some level 1 enemies) to be shades. Then with unfavorable race/class, gods and shop items it could be impossible to kill anything and impossible to get cursed so you can't access the shades.