Death Knight (Dracul inspired):
SANGUINE: 15% health regen on pool, +1 mana per pool, chugging manapotions boosts it.
DIAMOND BODY (undead body?): 50% starting physical resistance, 75% max cap
DETERMINED: 30% bonus damage when below 50% health
A fighter that benefits a lot from staying on low health, with controlled regeneration capabilities, highly benefitting from (almost) all of Dracul's boons. Regenning via pools allows it to cast low-cost glyphs, and to keep it's health high enough to tank, and B2P allows the Champion to keep it's health on controlled (below 50%) levels.
EDIT: I'm actually having a lot of fun mix and matching... Expect a lot more during the day. Probably god-thematic custom classes. Love the idea of those.
EDIT2:
Conduit (Mystera Annur inspired):
DRAGON BREATH: Fiery breath means normal attacks deal magical damage.
SPIRIT SWORD: Reaching conversion treshold drains mana and temporarily increases base damage (5+mana drained).
REFRESHMENT: Reaching conversion treshold regenerates 50% of your maximum mana.
(In this order.)
Thematic idea only. I have no clue how to actually leverage it.