A suggestion, regarding interface, and extra clicks :
It has been noted that some click are not useful (there is no choice behind them). There is for example the case of potions : we are likely to let them lie around the floor, and go on the top of them just to drink. So there should be a option to drink while they are on the floor (instead of clicking to pick them up, then click once more to drink). Or even worse : a right click on the tile where they are to move there, and drink them in one action. (1 click instead of 3)
I'll let you imagine any monster / feature causing potions left on the floor to disappear in some dungeons...