Assigning hotkeys, or hitting shift anything for that matter, is broken.
In the case of wizard tower level 1, shouldn't it be spelled story instead of storey?
In the quest where you must defeat the three goat lords, one of the dungeons will already have disappeared (as you beat it for the Taxidermy! quest). The problem is that the little quest info panel will still display that dungeon.
Is the delete confirmation box supposed to have text? It should probably say "Are you sure you want to delete this profile?"
Lastly, when you click a quest flag the dungeon and reward are grayed out until you mouse over them. Also, the random run button is always greyed out.
I speak chaos.