On the subject of Monk...
He is the most unintuitive character in the game and arguably a bit difficult to reach true potential with before you unlock everything (he goes full crazy with dragonshield). His true potential is a bit monstruous so you don't need to go that hard though...
What you want to do with him is stack resistances or base damage, prefferably both. If you can think moba's he's like those tanky carries which grow exponentialy with enough farm (or in this game's case, levels, items and boons).
For practice, simply prep Taurog, Fine Sword, then either Extra Glyph (for piety and a chance to run into Burndayraz, Apheelsick or Halpmeh early) or Extra Att boosters. Orc is probably your best bet (human's aren't bad either if you can secure base damage elsewhere, but orcs get early help and that's when he needs it). Then save your regen fighting helper glyph, convert for piety, grabe Taurogs toothpick and the Resistance items (either just the phys one or both), and you can even pick up the shield for a +20% att total which helps with your starting defficency. Go almost like playing warmonger and don't convert the poison and mana burn wards (regen fighters hate those). You probably won't need the DP chain, so feel free to leave taurog once youre happy with the gear (for say Drac, lol).
Then, err, destroy everything, pretty much. You can take a lot of hits, have 2X blackspace on the map, break fundamental rules like being able to fight a higher level monster AND beat it for regen during the fight... Add an apheelsick or burndaraz before you regen during the fight and, well, there you have it.
For true sillyness, you go Binlor and farm his magic resists while also grabbing his +30% dmg on wall destruction and +40 knockback while also prepping a bear mace. On an orc. With a Dragonshield possibly. So you kind of have no real downsides and can roflstomp vgt or naga city (provided you score a soul orb more or less).
For a completely different kind of insanity, go TT. Now if you can figure out how to do TT with Monk you're probably going to go far
(Takes crazy-ass lateral thinking and is not intuitive in the least bit). Essentially you want Dodging, possibly Tiki's Edge and 2-3 levels of poison then move to someone else. Then you have dodging and poison strike on a Monk O.O It takes shennanigans to get piety though (well, that or Fabulous Treasure and a load of tribute - it used to be piss-easy but they rightfully nerfed Tribute
). Best done if you join TT second and start with someone else, and then you can rejoin that deity later if need be.
As for regen fighting - it was way too good once upon a time so Halpmeh was nerfed, monk was nerfed, a lot of CP nonsense was nerfed and in the end the Trisword was nerfed. And TT poison was nerfed. (In case you're wondering, Paladin and Monk still go ahead of Warlord and Rogue on that list of Avatars, that's how good it is after all the nerfs. Before, you can imagine...)
So using it as a dedicated strategy is a bit harder these days (except with monks and paladins for who it's default mode). But the burning mechanic and the bloody sigil were introduced and poison was reworked, so it's best used a bit here and there (all the time for "cutting corners" or however we call it).
Sorry for verbose, manic textwall