I didnt finish Space Chem, been stuck on the second(?) last world on the boss... I cant figure out how to shoot at the asteroids fast enough... and didnt want to look up the solution, thats cheating

I devoured Manufactoria and all these other gems

Human Resource Machine looks intriguing! I have to try that one out.
I am still actively looking for a Puzzle City Builder. Something with the mechanics of SpaceChem, but with an overall increasing thing you have to optimally design and not single levels. I tried BigPharma, but didnt liked it... the puzzle part was too shallow. Does anyone know something like this?^^
Imagine a game, where you have houses with people, that need stuff. But when you produce stuff at a factory, the stuff does not get warped to the resource bar like always. Instead you have to build the logistic system behind with conveyor belts, traffic lights and so on (think SpaceChem) and guide the right resources to the right spot (maybe many work steps to the finished product before shipping it off). THATS a game I would INSTANTLY buy... but maybe I am alone with that^^