Gnome Transmuter (for obvious reasons)
Just visit your local alter of Jehora Jeheyu, and he'll set you right up
Elf Sorcerer (redundant; better off as Gnome 99% of the time)
Redundant != Bad
While I agree that this combo is overshadowed, it's by no means a bad
Elf Bloodmage (used to be a solid alternative to Gnomes; not so much now that their mana potions are utterly broken)
Some leeway is introduced thanks to the Crystal Ball, but with my Jehora/Mystera only unlock account it's completely ridiculous.
Orc Wizard (sans PISORF or Mana Leak + BICEPS, both of which make for powerful combos)
Orc Wizard needs to find either HALPMEH or PISORF. If he can get these he's golden, if he can't he's sub-optimal. I hardly consider that bad, especially given the Orc Rogue (prior to the CYDSTEPP neutering) was even more restrictive.
Best Fighter - Orc/Halfling
Worst Fighter - Gnome
Maybe I'm biased running a Jehora-based strategic deity unlock, but I have a great deal of difficulty calling gnomes the weakest race for any
class. I'd say Transmuter and Berserker are the only classes they're even in the running for the title of "weakest".
Best Assassin - Goblin
Worst Assassin - Gnome
You joking? Gnomish Assassin is a kick-ass caster. Between swift hands XP catapults and gnomish potions, his damage spiking potential is second-only to the Bloodmage.
I suspect that a JJ Gnome Assassin would rock pretty hard.
They do; I reproduced that Dragon Isles run with a JJ Gnome Assassin a few weeks back, and intend to do it again for my Half-Dragon unlock. (edit - just got it on the second try. Used Amulet of Yendor mid-battle to get to level 10, then used swift hands on her guards for a two milestones. Wasn't even close to running out of resources)
Anyways, Gnome/Elf Berserker/Monk is my vote for weakest combinations.